Hundreds of demonstrators marching from Sayeda Zeinab mosque to the Shura Council began clashing with security forces on the Corniche in front of the Shephard Hotel on Monday evening.
Protesters allegedly detained a police officer and began physically assaulting him before others intervened and stopped the attack.
Demonstrators also reportedly seized three armored police vehicles during the clashes, burning two of them in front of the hotel. A third was taken to Tahrir Square, where it was set on fire. A reporter for the privately owned ONTV satellite channel who was on the scene said that one of the vehicles hit two protesters, angering fellow demonstrators.
This comes after police launched a barrage of rubber bullets and teargas into the crowd.
The march was organized to demand the dissolution of the Shura Council, the suspension of the Constitution and the formation of a coalition government.
Political forces participating in the march include the Revolutionary Socialists Movement, the Socialist People's Alliance Party, the Popular Current, the Tagammu Party, the National Association for Change, the April 6 Democratic Front and the No to Military Trials movement.
The march is a continuation of protests that began on Friday, marking the second anniversary of the 25 January 2011 revolution.
Security was tightened around the Cairo municipality headquarters after demonstrators in Tahrir Square threatened to storm it and declare Cairo an independent province.